How Is Lanreotide Given
Lanreotide is injected under the skin.
A healthcare provider will give you this injection.
Lanreotide is usually given once every 4 weeks. Your doctor may occasionally change how often you receive injections.
Your blood sugar may need to be checked often, and you may need other blood tests at your doctor’s office.
Before Taking This Medicine
You should not use lanreotide if you are allergic to it.
Tell your doctor if you have ever had:
-
heart disease or
-
a thyroid disorder.
It is not known whether lanreotide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
This medicine may affect fertility in women.
You should not breast-feed while using lanreotide and for at least 6 months after your last dose.
How Long Can You Take Lanreotide
4.3/5Lanreotide isshouldLanreotide is
Considering this, how long do the side effects of lanreotide last?
Side effects such as diarrhea, bloating, gas, and abdominal pain were reported in studies. It is difficult to tell if these are related to the medication or the disease, so discuss them with your doctor or nurse. If these occur, they typically stop within 1-4 days of the injection and decrease with long-term treatment.
One may also ask, does Lanreotide cause hair loss? hair loss. pain in the injection site. liver changes that are unlikely to cause you problems. changes in blood sugar levels.
Also asked, what are the side effects of lanreotide?
Side effects of Somatuline Depot include headache, nausea, vomiting, diarrhea, constipation, stomach pain, gas, weight loss, joint pain, or injection site reactions . Somatuline Depot injection is administered every 4 weeks as directed by your doctor.
How much does Lanreotide cost?
The estimated per-cycle costs of a somatostatin analog treatment were $5241.73 for 30-mg octreotide LAR and $6000 for 120-mg lanreotide, based on the ReadyPrice Wholesale Acquisition Cost, which was accessed on July 17, 2016.
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Warning Disclaimer Use For Publication
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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What Are Some Things I Need To Know Or Do While I Take This Drug
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- This drug may cause dizziness. If this happens, do not drive or do other tasks or actions that call for you to be alert. Talk with your doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- High or low blood sugar may happen in some patients after this drug is given. Talk with the doctor.
- Check your blood sugar as you have been told by your doctor.
- High blood pressure has happened with this drug. Have your blood pressure checked as you have been told by your doctor.
- Gallbladder problems have happened. Sometimes, people had to be treated in the hospital. In some cases the gallbladder had to be removed. Discuss any questions with the doctor.
- This drug may cause fertility problems. This may affect being able to have children. Talk with the doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
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What Other Information Should I Know
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body’s response to lanreotide injection.
Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Effects On Ability To Drive And Use Machines
Somatuline Autogel has minor or moderate influence on the ability to drive and use machines. No studies on the effects on the ability to drive and use machines have been performed. However, dizziness has been reported with Somatuline Autogel. If a patient is affected he/ she should not drive or operate machinery.
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What Is Somatuline Autogel Used For
Somatuline Autogel is used for the treatment of acromegaly when the circulating levels of growth hormone and IGF-1 remain abnormal after surgery and/or radiotherapy, or in patients who do not respond to therapy with drugs called dopamine agonists.
Somatuline Autogel is used for the treatment of symptoms associated with carcinoid syndrome, such as flushing and diarrhoea.
Somatuline Autogel is used for the treatment and control of the growth of some advanced tumours of the intestine and pancreas that cannot be removed by surgery .
How Often Do You Have Lanreotide
You usually start having lanreotide injections every 2 to 4 weeks. Depending on your symptoms, your doctor might change the amount and length of time between your injections.
If you are having lanreotide to control the growth of your NET, you continue this for as long as it is working, and the side effects arent too bad.
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Tips For Hair Loss Or Thinning
- Use gentle hair products such as baby shampoos.
- Don’t use perms or hair colours on thinning hair colours may not take well and perms can damage the hair.
- Use a soft baby brush and comb thinning hair gently.
- Avoid using hair dryers, curling tongs, hair straighteners and curlers on thinning hair and pat your hair dry after washing.
- If your scalp flakes or itches this means it is dry use oil or moisturiser, not dandruff shampoo.
- Protect your scalp by covering your head in the sun.
Effect Of 1224 Months Of Oct
A remarkable decrease in tumor volume was observed in de novo patients during OCT-LAR treatment . After 3 months only five patients had a mild-to-moderate shrinkage. In contrast, at the last follow-up shrinkage was absent in three patients , mild in three , moderate in six , and notable in three patients. Two patients with microadenoma had disappearance of their tumors after 612 months of treatment. In one patient with microadenoma a remarkable tumor decrease was observed after 3 months of OCT-LAR treatment at a dose of 20 mg every 28 days . Tumor shrinkage was evaluated in only 9 of the 21 operated patients : shrinkage was absent in 4, mild in 1, moderate in 3, and notable in 1 patient. After 12 and 24 months of treatment, no difference was found in the maximal tumor diameter both in the eight de novo and in the nine operated patients . At the last follow-up, the decrease in the maximal tumor diameter was slightly but not significantly higher in de novo than in operated patients . In de novo patients, no correlation was found between tumor volume and age, disease duration and baseline GH and IGF-I levels, or between the percent tumor reduction and percent GH/IGF-I suppression or the dose of OCT-LAR. No patient had tumor reexpansion during OCT-LAR treatment. No de novo patient had visual field defects at study entry whereas 4 of the 21 operated patients had temporal quadrantopsia that did not significantly improve during OCT-LAR treatment.
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What Form Does This Medication Come In
60 mg/0.5 mL Each 0.5 mL prefilled syringe of extended release solution contains 60 mg of lanreotide as lanreotide acetate. Nonmedicinal ingredients: glacial acetic acid and water for injection.
90 mg/0.5 mL Each 0.5 mL prefilled syringe of extended release solution contains 90 mg of lanreotide as lanreotide acetate. Nonmedicinal ingredients: glacial acetic acid and water for injection.
120 mg/0.5 mL Each 0.5 mL prefilled syringe of extended release solution contains 120 mg of lanreotide as lanreotide acetate. Nonmedicinal ingredients: glacial acetic acid and water for injection.
What Is The Most Important Information I Should Know About Lanreotide
You should not use lanreotide if you are allergic to it.
Tell your doctor if you have ever had:
- gallbladder disease
- diabetes
- liver or kidney disease
- heart disease or
- a thyroid disorder.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
This medicine may affect fertility in women.
You should not breast-feed while using lanreotide and for at least 6 months after your last dose.
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What Other Drugs Will Affect Lanreotide
When you start or stop taking lanreotide, your doctor may need to adjust the doses of any other medicines you take on a regular basis.
Tell your doctor about all your other medicines, especially:
- beta-blocker heart or blood pressure medicine .
This list is not complete. Other drugs may affect lanreotide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
What Are The Possible Side Effects Of Lanreotide
Get emergency medical help if you have signs of an allergic reaction: hives difficult breathing swelling of your face, lips, tongue, or throat.
- headache, dizziness or
- pain, itching, or a hard lump where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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How Do Drugs Cause Hair Loss
Drugs cause hair loss by interfering with the normal cycle of scalp hair growth. During the anagen phase, which lasts for two to seven years, the hair grows. During the telogen phase, which lasts about three months, the hair rests. At the end of the telogen phase, the hair falls out and is replaced by new hair.
Medications can lead to two types of hair loss: telogen effluvium and anagen effluvium. Learn more about other causes of baldness.
Telogen effluvium is the most common form of drug-induced hair loss. It usually appears within 2 to 4 months after taking the drug. This condition causes the hair follicles to go into their resting phase and fall out too early. People with telogen effluvium usually shed between 30% to 70% more than the normal 100 and 150 hairs a day.
Anagen effluvium is hair loss that occurs during the anagen phase of the hair cycle, when the hairs are actively growing. It prevents the matrix cells, which produce new hairs, from dividing normally. This type of hair loss usually occurs within a few days to weeks after taking the medication. It’s most common in people who are taking chemotherapy drugs for cancer and is often severe, causing people to lose most or all of the hair on their head, as well as their eyebrows, eyelashes, and other body hairs.
The severity of drug-induced hair loss depends on the type of drug and dosage, as well as your sensitivity to that drug.
How Does Lanreotide Work
Somatostatin is a hormone made naturally in the body. It slows down or stops the production of a number of hormones such as insulin and gut hormones. It also controls the emptying of the stomach and bowel.
Lanreotide is a synthetic version of somatostatin and slows down the production of hormones. This helps to control the symptoms of carcinoid syndrome and slow down the growth of the cancer.
Some of the symptoms you may have with carcinoid syndrome include flushing of the skin, diarrhoea, and tummy pain.
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About Hair Loss Or Hair Thinning
Hair loss is one of the most well known side effects of cancer treatment. For many people losing their hair can be distressing and devastating.
It can be a constant reminder of your cancer and what youre going through. But for most people, their hair will grow back once treatment has finished.
Cancer drugs can cause:
- mild thinning of your hair
- partial hair loss, or loss of patches of hair
- complete hair loss
Chemotherapy is the type of cancer drug treatment most likely to cause hair loss.
Complete hair loss is very unlikely with any other type of treatment. But some other cancer drugs can cause hair thinning. It is not possible to tell beforehand who will be affected or how badly.
Hair loss also depends on factors such as:
- the type of drug or combination of drugs you are taking
- the dose
- the route
- how sensitive you are to the drug
- your drug treatment in the past
Magnetic Resonance Imaging Studies
MRI studies were performed on clinical 0.5T and 1T scanners, using T1-weighted gradient recalled-echo in the sagittal and coronal planes. In each measurement 711 slices were obtained, with a slice thickness of 23 mm and an in-plane spatial resolution of 0.70.97 mm . The acquisitions were repeated before and after the administration of 0.1 mmol gadolinium chelate . MRI was performed before and after 3, 6, 12, and 24 months of OCT-LAR treatment in de novo patients and before and after 12 and 24 months in operated patients. In de novo patients shrinkage was established on tumor volume calculated by the Di Chiro and Nelson formula: volume = height × length × width × /6 and on the maximal tumor diameter, whereas in patients previously operated on shrinkage was established only on the maximal tumor diameter. Tumor shrinkage was evaluated as a reduction of the pretreatment tumor volume or maximal tumor diameter, respectively, in a semiquantitative way as: less than 25% or less than 10%, no shrinkage 2650% or 1120%, mild shrinkage 5175% or 2130%, moderate shrinkage more than 75% or more than 30%, notable shrinkage. The radiologist was blind in respect to the status of the patient.
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When To Contact Your Team
Your doctor or nurse will go through the possible side effects. They will monitor you closely during treatment and check how you are at your appointments. Contact your advice line as soon as possible if:
- you have severe side effects
- your side effects arent getting any better
- your side effects are getting worse
Why Is This Medication Prescribed
Lanreotide injection is used to treat people with acromegaly who have not successfully, or cannot be treated with surgery or radiation. Lanreotide injection is also used to treat people with neuroendocrine tumors in the gastrointestinal tract or the pancreas that have spread or cannot be removed by surgery. Lanreotide injection is in a class of medications called somatostatin agonists. It works by decreasing the amounts of certain natural substances produced by the body.
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