Krox20 Protein Scf Gene
Researchers from University of Texas Southwestern Medical Center in Dallas have identified a protein called KROX20, which switches on cells in the skin and tells them to become hair. Furthermore, these hair precursor cells then go on to produce a protein called stem cell factor , which plays a critical role in hair pigmentation.
When the SCF gene was deleted in the hair precursor cells in mice, they grew gray hair that turned white with age. Moreover, when the KROX20-producing cells were removed, the hair ceased growing, and the mice became bald.
With this knowledge, we hope in the future to create a topical compound or to safely deliver the necessary gene to hair follicles to correct these cosmetic problems, said Dr. Lu Le, associate professor of dermatology at UT Southwestern.
Future work by the team will focus on finding out whether KROX20 and the SCF gene stop functioning properly and lead to male pattern baldness.
What Shampoo Should I Use For Thinning Hair
Because thinning hair can happen for a number of different reasons, you might have to go through a trial-and-error period to find the shampoo that works best for you.
Some shampoos are aimed at reducing hair loss, while others aim to thicken existing hair.
Prescription-strength shampoo for thinning hair is also an option that you can speak with your doctor about.
When Hair May Regrow On Its Own
Yes, your hair may regrow on its own. This can happen if you recently:
Had a baby
Recovered from a major illness or had surgery
Underwent cancer treatment
Lost 20 pounds or more
Developed a mild case of a disease called alopecia areata, which causes your immune system to attack your hair follicles
Got rid of psoriasis on your scalp
Your dermatologist can tell you whether your hair may start to grow again on its own.
Sometimes to see regrowth, you need to make some changes.
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Are There Potential Side Effects
Minoxidil users report few side effects, and when they do, those reports usually include scalp irritation and mild discomfort. Most men find that the solution form of minoxidil is more likely to cause adverse reactions than the foam, and the foam is a bit easier to apply. Thats one of the reasons we like Keeps, as they have the best deal on the foam form of minoxidil. If you notice severe discomfort, you should speak with a physician.
You need to wash your hands thoroughly after applying minoxidil to your scalp and wait several hours before touching your application area or going to bed after applying it. Until its completely dry, minoxidil can spread and absorb in places where it may cause unwanted hair to grow.
As minoxidil works, it can shift the growth phases of your follicles, causing some of them to prematurely shed their current, weakened strands and begin growing thicker, stronger ones. This process usually kicks in several weeks into treatment, and at the outset, you may experience a heightened degree of shedding. This additional hair loss is actually a sign that the minoxidil is working. Dont stop your minoxidil routine if you experience this side effect, as it is temporary, and a phase of healthy growth will soon follow.
Hair Fall Prevention Tips
- Switch to a balanced diet.
- Get adequate sleep.
- Steer clear of tight hairstyles.
- Pop a multivitamin tablet.
- Cover your hair with a scarf when you are out in the pollution.
- Stay away from hair styling techniques as much as possible.
- Regular oil massages will calm the mind, relieve stress and strengthen the roots.
- Washing hair with hot water can cause hair fall. Cool water is always recommended for hair wash.
Restrict the application of shampoo to the hair to a minimum. Shampoo can be used to wash the dirt off the scalp. Don’t apply conditioner to the scalp but to the hair length starting from your ears. Conditioners can form a protective layer against pollution.
Read Also: Which Hair Loss Treatments Work
How Many Treatments Are Needed
The number of hair loss treatments required will vary from patient to patient. Some patients see only a slight improvement in hair growth after one course of hair loss treatment, while others may require multiple courses of platelet-rich plasma therapy before experiencing the desired results.
It’s important to keep in mind that platelet-rich plasma is not a permanent solution and will eventually need to be repeated if you want to preserve your hair. However, the results of platelet-rich plasma therapy do last longer than most forms of hair loss treatment for this reason, it is an excellent option if you aren’t ready to commit to a permanent change in your appearance.
Better Not Younger Superpower Hair & Scalp Duo
- Price: $$$
The Better Not Younger Hair and Scalp Duo includes a hair and scalp serum with ingredients like niacinamide, caffeine, and gotu kola. It also boasts a scalp massaging applicator to help distribute the serum.
While its on the higher end of our pricing scale, youre essentially extending the bang for your buck by getting two products in one set.
According to the Better Not Younger website, 97 percent of women using the serum daily for 8 weeks in independent consumer trials saw improvements in hair quality and hair fall.
The action of massaging the scalp with the scalp massaging applicator may provide additional benefits.
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Womens Rogaine 5% Unscented Minoxidil Foam
- Price: $$$$
Rogaine is an FDA approved treatment for hair loss that contains minoxidil. It generally contains a stronger percentage than other OTC brands, and its one of the most popular and well-known for good reason.
The brand offers a satisfaction guarantee policy, which means youll get a full refund if you use the product daily for 130 days and arent satisfied with the results. For best results, its recommended to use Rogaine for at least 3 to 6 months to see results.
When it comes to reviews, a majority of reviewers note that their hair grew in spots where their scalp was visible before. On the other hand, a few 1-star reviews have to do with allergic reactions, scalp sensitivity, no changes, or even increased hair loss.
Its important to note that minoxidil may cause initial shedding, but this effect will likely decrease with use.
What Works For Hair Loss Effective Solutions For Thick And Healthy Hair
Do you wonder what works for hair loss? Here are effective and safe solutions to help you have thick hair without nasty side effects to your health.
Are you worried about your hair falling out a lot?
If you are bothered about hair fall, and you need to know what works for hair loss, this post may just help you.
We investigate what makes up the hair, what causes it to fall, and what can be done to address hair loss safely and effectively.
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Treatment Options For Androgenetic Alopecia
Melissa C. Jones, PharmD, BCPSAssistant Dean for AdmissionsSavannah, Georgia
US Pharm. 2018 43:12-16.
ABSTRACT: Androgenetic alopecia , or male pattern baldness, is the most common cause of hair loss in men. There are several therapies available for the treatment of this condition, with 5-alpha reductase inhibitors and minoxidil most commonly used. Other current treatment options include laser therapy, scalp microneedling, hair mesotherapy, and hair transplantation. The development of new pharmacologic therapies has been slow however, research is currently being conducted using Janus kinase inhibitors and autologous platelet-rich plasma injections in men with AGA.
Androgenetic alopecia , or male pattern baldness, is a common condition that causes many men to seek medical attention. It is characterized by hair follicles that gradually decrease in size and lead to baldness over time. AGA affects approximately 80% of Caucasian males. Although it is common in men of different ethnic backgrounds, Caucasian males are affected more frequently.1 Traditionally, pharmacologic treatment of AGA targets decreasing dihydrotestosterone and stimulating hair follicles through the use of 5-alpha reductase inhibitors or minoxidil however, new and experimental therapies are exploring inhibition of Janus kinase and the use of platelet-rich plasma . Other therapies include laser therapy, scalp microneedling, hair mesotherapy, and hair transplantation.1
What Are The Long
Since these are experimental PRP treatments, there is not yet enough data on their long-term effects to determine whether there are any associated risks.
That said, many patients have experienced long-term benefits that allow them to retain their results for several months or more. Studies also show that PRP is effective in stimulating hair growth and visibly improving the quality of affected hair after multiple PRP treatments.
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What Are Lllt Devices And How Do They Work
You may have seen laser hair loss devices advertised on TV or online. Some look like ballcaps, others like helmets or strange hair decorations that fit like a wedge over a portion of your head. Others take the shape of combs that you slowly run through your hair in the thinning area.
All of them glow red , and all of them claim to help you stop your hair loss and potentially regrow hair.
These devices glow red because they rely on low-level laser diodes to promote vasodilation and stimulate blood flow. Low-level laser therapy is sometimes called cold laser therapy or photobiomodulation. Wavelengths of these lasers range from about 600 to 1100 nanometers in hair growth products, with a wavelength of roughly 655 nm included in the bulk of scientific research.
To be clear, these are not simple LEDs. Laser diodes are more precise and more powerful than LEDs. There are some cut-rate products on the market that claim to stop hair loss with LEDs. Beware of these, as they are pure examples of charlatanism.
Researchers who have studied the effectiveness of LLLT theorize that several mechanisms might be at play in achieving hair regrowth. One of the likeliest is that the powerful laser light penetrates to a deep layer of the scalp. It effectively improves blood flow to follicles, allowing them to benefit from increased oxygen and nutrients delivered by our blood.
What Actually Works For Hair Loss And Whats Just Marketing
Knowing how to treat hair loss is tricky when so many different products on the market claim to promote regrowth.
Two doctors explain which ingredients and treatments are most effective.
Familiarizing yourself with the treatment options is the best way to differentiate between what actually works and whats just marketing.
In beauty, we know some things to be absolutely true like hyaluronic acid is good for plumping, and vitamin A helps promote cellular turnover. And then there are the gray, slightly murky areas of the industry like if topical products actually help with hair loss.
First, its important to note the issues prevalence: one in five people are affected by hair loss in the US, according to the International Society of Hair Restoration Surgery. With that said, its causes and how it manifests look different it might be a byproduct of hormonal changes, a gradual thinning, or even a side effect of the COVID-19 virus. Regardless, its a common condition that can be distressing for many.
As a result, theres been an increase in products, from scalp serums to shampoo and conditioner duos, that claim to help treat hair loss by promoting hair regrowth. However, its hard to tell which ones are actually worth it, and whats just marketing. To better understand what ingredients actually help, we spoke to two doctors. Keep reading for their advice.
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What Are Beard Fillers
Beard fillers, much like hair fillers that you use on your scalp, are designed to make your beard look thicker. Fillers dont help your hair grow any faster, and bad ones can actually prohibit your hair growth a little. But a filler is just that, something that fills in the thin areas and nothing more.
Depending on the type of beard filler used, the filler can do more than just fill in thin spots, though. For example, filler pencils can add shape to your beard or define the edges for a sharper contrast. There are three main types of beard fillers.
These three are: pencil fillers, pen fillers, and powder fillers. Each type of beard filler has its own advantages and disadvantages, so any one might work best for you. All types of beard fillers come in different colors so that you can get a filler the color you need.
If in doubt, fillers tend to work best when they are a shade too dark rather than a shade too light. The darker color makes a shadow effect giving the illusion of depth. Though not a dye, some beard fillers can be used to hide grey hair.
Light blonde hair is slightly harder to find fillers for, but there are options out there. There are even white or grey fillers if you happen to have one of those solid white beards or are grey. Good reddish beard fillers are also a little less common to see.
Low Maintenance Is Key
If given a choice, most men likely wouldnt mind putting in a little effort if it meant keeping or even regrowing their hair. But you need to know yourself and your habits to understand which treatment option will be low-maintenance enough for you to see it through. Finasteride and minoxidil are forever treatments, which means that you have to keep using them for them to work. As soon as you suspend either medication, your hair loss will come back.
Between the two, oral finasteride is easier to use daily than minoxidil. You take a pill without having to apply anything to your scalp. There are trade-offs here, of course, such as the side effect profile. And if the side effects are too significant for you to continue treatment, youd have been better off with the more cumbersome daily routine.
Among non-medicinal options like the replacement methods provided by HairClub, you can get instant results that require infrequent trips to a clinic or a more dramatic surgery that can require little to no maintenance moving forward.
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Coping With Hair Loss
The emotional impact of hair loss will vary greatly from person to person.
Some people may wish to seek counseling services as part of their treatment. Others may choose a hairstyle that embraces hair loss, such as a shaved head.
Hair loss may affect a persons self-esteem and lead to depression and reduced quality of life.
If a person notices a decline in their quality of life after the onset of hair loss, they should seek support from a medical professional.
People should contact a doctor if they experience any of the following:
- sudden hair loss
- hair falling out in clumps
- itching or burning scalp
People should also contact a healthcare professional if they are worried about their hair loss.
A healthcare professional may ask questions or perform tests to investigate whether the hair loss is a result of:
- an illness
The following are some frequently asked questions about hair loss: