What Is Cimzia Used For
If you have certain conditions, your doctor may recommend that you take Cimzia. Its used for people ages 18 years and older, to treat the following long-lasting conditions:
- Plaque psoriasis . With PsO, you have inflammation in your skin. You may have pink or dark-colored patches with scales. These may appear on your scalp, elbows, knees, and lower back. Any part of your body can be affected by PsO.
- Crohns disease .CD is an inflammatory bowel disease that can affect your entire digestive system. Most people with CD have inflammation in their intestine.
- Rheumatoid arthritis . With RA, you have swollen, painful joints. Usually, youll have swelling in the small joints of your hands and the wrist. Other joints that may be affected by RA include the knees, ankles, elbows, shoulders, and hips.
- Psoriatic arthritis . With PsA, you have swelling in your joints and your skin. This disease shares many features of both RA and PSO.
- Ankylosing spondylitis .AS is an inflammatory disease that affects the spine. People with AS usually have long-lasting lower back pain and stiffness in their spine.
- Non-radiographic axial spondyloarthritis. With non-radiographic axial spondyloarthritis, you have symptoms consistent with AS. But unlike AS, you dont have inflammation on your lower spine that can be seen on radiographs .
What Is Similar To Cimzia
- Humira.
- Cosentyx.
- Stelara.
Does Cimzia cause hair loss? Cimzia may cause a rare type of hair loss known as alopecia totalis, a complete loss of hair on the scalp. The cause for the hair loss may be due to an immune-system reaction while using Cimzia.
What diseases does Cimzia treat?
What is Certolizumab ? Certolizumab pegol is a drug that reduces the signs and symptoms of moderate to severe rheumatoid arthritis , psoriatic arthritis , ankylosing spondylitis, and Crohns disease.
Is Cimzia a biologic? The Logic of a Biologic Medication Like CIMZIA
CIMZIA is a biologic, meaning its made by or from living cells. More specifically, its an anti-TNF . TNF is a natural substance in your body that signals immune cells to fight infections and disease.
What Is The Most Important Information I Should Know About Cimzia
You should not use certolizumab if you are allergic to it. You may not be able to use certolizumab if you have symptoms of an infection such as fever, chills, cough, skin sores, shortness of breath, weight loss, diarrhea, or painful urination.
Tell your doctor if you have ever had tuberculosis or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.
Certolizumab may cause a rare type of lymphoma of the liver, spleen, and bone marrow that can be fatal. This has occurred mainly in teenagers and young men with Crohn’s disease or ulcerative colitis. However, anyone with an inflammatory autoimmune disorder may have a higher risk of lymphoma. Talk with your doctor about your own risk.
Tell your doctor if you have ever had:
- a chronic infection
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Can I Take Cimzia If I Have Diabetes
Yes, but you may be more at risk of getting infections. Both diabetes and Cimzia can raise your risk for getting infections. To help avoid infections:
- make sure all your immunizations are up to date before you start Cimzia
- get the flu shot every year
- if possible, stay away from people who have an infection
- wash your hands often
- practice good foot care to avoid foot ulcers and infections
See your doctor right away if you get any symptoms of an infection while youre taking Cimzia.
How Often Is Cimzia Administered
The recommended dose of CIMZIA for adult patients with rheumatoid arthritis is 400 mg initially and at Weeks 2 and 4, followed by 200 mg every other week. For maintenance dosing, CIMZIA 400 mg every 4 weeks can be considered .
Is there a generic for Cimzia? Generic Name: certolizumab pegol.
What is Cimzia indicated for?
CIMZIA is indicated for reducing signs and symptoms of Crohns disease and maintaining clinical response in adult patients with moderately to severely active disease who have had an inadequate response to conventional therapy.
Is Cimzia similar to Enbrel? Are Enbrel and Cimzia the Same Thing? Enbrel and Cimzia are both tumor necrosis factor inhibitors used to treat different conditions.
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What About Other Medications
When you are taking certolizumab, it is very important that your doctors know if you are taking any other medicine. This includes prescription and non-prescription medicines as well as birth control pills, vitamins, and herbal supplements. Certolizumab can be taken with other medications NSAIDS , prednisone, methotrexate, and plaquenil. You should not take certolizumab with other TNF-blockers, or other biologic drugs used to treat RA.
Cimzia For Plaque Psoriasis
Cimzia is FDA-approved to treat plaque psoriasis in adults. Its used for moderate to severe plaque psoriasis that could benefit from systemic treatment or .
Plaque psoriasis is the most common type of the skin condition psoriasis. Its an autoimmune disease . It causes red or silver plaques to develop on your skin. Cimzia helps reduce the number of psoriasis plaques and how severe they are.
Effectiveness for plaque psoriasis
In clinical studies, Cimzia was more effective than a placebo at reducing symptoms of plaque psoriasis. After 16 weeks:
- 45% to 65% of people who took Cimzia had minimal psoriasis symptoms or saw their symptoms clear up. Of those who took a placebo, 3% to 4% of people had the same result.
- 65% to 82% of people who took Cimzia had at least a 75% improvement in their psoriasis symptoms. Of those who took a placebo, 4% to 13% had the same result.
Results were similar after 48 weeks of treatment.
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Cimzia: Serious Side Effects
Its possible to have serious side effects with Cimzia. Serious side effects are listed below, but this list may not include all possibilities. To learn more about Cimzias side effects, view the drugs prescribing information.
Serious side effects of Cimzia and their possible symptoms include:
You may have a higher risk of serious infections with Cimzia if any of the above apply to you.
Your doctor will test you for TB before prescribing Cimzia. If the test is positive, theyll treat the TB before having you start Cimzia. Theyll also monitor you for TB and other infections during Cimzia treatment.
If you develop symptoms of an infection while taking Cimzia, call your doctor right away. Theyll likely have you stop taking Cimzia and prescribe treatment for your infection.
White Paper: It’s Time To Start Prescribing Biosimilars
The American College of Rheumatology’s new white paper, The Science Behind BiosimilarsEntering a New Era of Biologic Therapy, encourages physicians to begin integrating biosimilars in patient treatment, where appropriate.
Biosimilar integration into prescription patterns provides more options for patientshopefully at a lower costand improves access to more patients who could benefit, says lead author S. Louis Bridges Jr., MD, PhD, Anna Lois Waters Endowed Chair and director of the University of Alabama at Birmingham’s Division of Clinical Immunology and Rheumatology, in a release. Faculty members in our division are leading national discussions on biosimilars in the treatment of rheumatic diseases, and we’re proud to be a part of this.
While biosimilar medications are newer to the American marketplace, they have been successful in their usage in other countries for many years. Currently, the FDA has approved nine biosimilar medications, six of which are used to treat rheumatic diseases including psoriatic arthritis.
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What Should I Know About Cimzia Vs Humira
Cimzia and Humira are both used to treat some of the same conditions. They have some of the same side effects and risks. But these drugs also have some differences.
To see a breakdown of how Cimzia and Humira are alike and different, view our Cimzia vs. Humira article.
Find answers to some commonly asked questions about Cimzia.
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Is Cimzia A Black Box Drug
The Cimzia drug label comes with the following Black Box warning: Patients treated with Cimzia are at an increased risk of serious infections leading to hospitalization or death including tuberculosis , bacterial sepsis, invasive fungal infections , and infections due to other opportunistic
Does cimzia cause hair loss?
Cimzia may cause a rare type of hair loss known as alopecia totalis, a complete loss of hair on the scalp. The cause for the hair loss may be due to an immune-system reaction while using Cimzia.
Is cimzia a black box drug? The Cimzia drug label comes with the following Black Box warning: Patients treated with Cimzia are at an increased risk of serious infections leading to hospitalization or death including tuberculosis , bacterial sepsis, invasive fungal infections , and infections due to other opportunistic
What is Cimzia FDA approved for? Cimzia FDA Approval History
Cimzia is a PEGylated anti-TNF biologic therapy for the treatment of Crohns disease, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, plaque psoriasis, and non-radiographic axial spondyloarthritis.
Side Effects Not Requiring Immediate Medical Attention
Some side effects of certolizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Applies to certolizumab: subcutaneous kit
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How To Stop Hair Loss Associated With Medication
If hair loss is affecting your appearance and self-confidence, your healthcare provider may try to lower your dosage or switch you to another medication to see if that solves the issue.
If the medication is effectively treating your arthritis, your practitioner may discuss with you the benefits and side effects before taking such measures.
When altering the dose or switching medications isnt possible, your practitioner may refer you to a dermatologist for other options.
Cimzia: What To Discuss With Your Doctor
Talk with your doctor or pharmacist to find out more about Cimzia. If you have questions about the drugs side effects, your pharmacist or healthcare professional can help answer them for you.
In addition to discussing Cimzia with your doctor, you may find the following articles helpful in learning more.
- Overview of Cimzia. To read an overview of Cimzia, see this article.
- Drug comparison. To learn how Cimzia compares with Humira, read this article.
- Details about Cimzias uses. To learn more about the conditions Cimzia is used to treat, see the articles below:
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Cimzia And Other Medications
Below is a list of medications that can interact with Cimzia. This list does not contain all drugs that may interact with Cimzia.
Before taking Cimzia, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.
If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.
Cimzia and immunosuppressant drugs
Immunosuppressants are drugs that weaken your immune system. Cimzia can also weaken your immune system. Taking Cimzia with an immunosuppressant can raise your risk for getting infections.
Examples of immunosuppressant drugs that can raise the risk of infections with Cimzia include:
- corticosteroids such as prednisone
- methotrexate
Cimzia and certain other biologics
Cimzia is a biologic . Cimzia is not recommended with other biologics used to treat arthritis, Crohns disease, or psoriasis because it raises your risk for serious infections.
Examples of other biologics that are not recommended for use with Cimzia include:
Its safe to get inactive vaccines, such as the flu shot, while youre using Cimzia.
Why Arthritis Medications Can Cause Hair Loss
The primary group of medications that may cause hair loss would be DMARDs , particularly methotrexate, says San Francisco rheumatologist Nancy Carteron, MD, who is part of the clinical faculty at the University of California, San Francisco .
The way these DMARDs work can put hair cells in the line of fire. In order to control arthritis, we use medications that limit the growth rate of hyper-active immune cells, which arise from the bone marrow. Apart from bone marrow, hair is the fastest-growing tissue in the body, says Dr. Blazer. As one can imagine, using a strategy that limits the growth of fast-replicating tissues may also influence the hair.
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Can I Take Cimzia If Im Pregnant Or Breastfeeding
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant. Your name may be listed on a pregnancy registry to track the effects of certolizumab on the baby.
It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.