Does Aimovig Cause Weight Loss
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Which One Works Better
Its too soon to know if one treatment is more effective for any given situation. We just dont know if one works better than others for specific types of Migraine, or certain populations based on age, gender, or comorbidities. Getting those answers will require years of observing patient responses to treatment.
David Watson, MD, shares his perspective on these new treatment options:
It is still way too early to determine which of these new medications is better, or even if there is real difference. Like most treatment options, what works for one person perfectly might not be so great for someone else. The big news here is that we have three new treatment options, all of which appear to be effective for preventing migraine attacks. Thats great news.
Nature And Contents Of Container
Aimovig is provided as:Carton of two* 70 mg/mL prefilled syringe with Type 1 glass syringe and stainless steel needle.Carton of one* , two* or six* 70 mg/mL prefilled pen SureClick autoinjector with Type 1 glass syringe and stainless steel needle.Carton of one* 140 mg/mL prefilled SureClick autoinjector with Type 1 glass syringe and stainless steel needle.* Not all pack sizes or presentations may be marketed.The needle shield within the white or orange cap of the prefilled autoinjector and the gray needle cap of the prefilled syringe contain dry natural rubber .
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Instructions For Taking Aimovig
Your doctor will show you how to give yourself Aimovig injections. You can also watch a video with step-by-step instructions for injecting Aimovig on the drug manufacturers website. You can also read Aimovigs prescribing information.
Questions for your doctor
You may have questions about Aimovig and your treatment plan. Its important to discuss all your concerns with your doctor.
Here are a few tips that might help guide your discussion:
- Before your appointment, write down questions such as:
- How will Aimovig affect my body, mood, or lifestyle?
Bring someone with you to your appointment if doing so will help you feel more comfortable. If you dont understand something related to your condition or treatment, ask your doctor to explain it to you. Remember, your doctor and other healthcare professionals are available to help you. And they want you to get the best care possible. So dont be afraid to ask questions or offer feedback on your treatment.
Before taking Aimovig, its important to talk with your doctor about other medical conditions you have and your overall health.
These and other considerations are discussed below in more detail.
Aimovig Is Considered After Trying Other First
“Aimovig is a new treatment, and there are still many unanswered questions about safety,” explains Dr. Burch. “Given this, we are offering Aimovig to patients who have failed or who have contraindications to three other preventive treatments. We usually try oral preventives with high levels of evidence for efficacy in the preventive treatment guidelines. Amitriptyline, topiramate, and propranolol are often used as first-line treatments. These criteria are also what we typically use when we consider onabotulinum toxin in patients with chronic migraine. Aimovig wasn’t studied in children, or in older adults, so we use more caution in those populations.”
The American Headache Society Position Statement On Integrating New Migraine Treatments Into Clinical Practice. . Headache.59, 1-18.
Talk with your healthcare provider to determine if it’s a good fit for you.
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Other Uses For Aimovig
In addition to preventing migraine, which is discussed in the section just above, Aimovig may also be used off-label for other conditions. Off-label use is when a drug thats approved to treat one condition is prescribed to treat a different condition.
Below, we describe two off-label uses for Aimovig.
Aimovig for cluster headaches
Aimovig is not FDA-approved to prevent cluster headaches, but it may be used off-label for this purpose. Its not currently known if Aimovig is effective at preventing cluster headaches.
Cluster headaches are painful headaches that occur in clusters . They can be either episodic or chronic. Episodic cluster headaches have longer periods of time between clusters of headaches. Chronic cluster headaches have shorter periods between headache clusters.
Aimovig hasnt been tested in clinical studies to prevent cluster headaches.
But Emgality, a drug that belongs to the same class of medications as Aimovig, has been approved to treat episodic cluster headaches. In one clinical study, Emgality was found to help treat episodic cluster headaches.
Aimovig for vestibular headaches
Aimovig is not FDA-approved to prevent or treat vestibular headaches. Vestibular headaches are different from classic migraine headaches because theyre usually not painful. People with vestibular headaches may feel dizzy or experience vertigo. These symptoms may last seconds to hours.
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How Does This Medication Work What Will It Do For Me
Erenumab belongs to the class of medications called calcitonin gene-related peptide receptor antagonists. Erenumab is used to prevent migraine for adults who experience 4 or more migraine days each month.
This medication works by blocking the activity of a protein called calcitonin gene-related peptide. For people suffering a migraine attack, this protein is increased.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
Comparable Early Results To Aimovig
For comparative purposes, the following is a recap of early results found with the authors outpatient clinic use of Aimovig for the prevention of chronic migraine.
In that evaluation, the author assessed 220 chronic migraine patients who had been prescribed Aimovig. Efficacy and side effects were evaluated after 3 months. Slightly less than 60% of the patients reported at least 30% relief. Approximately 24% of the patients reported 70 to 100% relief. The response after 2 months generally was predictive of response after 6 months of treatment. Most of the patients who utilized frequent opioids at baseline did not do well with the Aimovig. If patients had moderate or severely refractory chronic migraine, they generally did not do well with the Aimovig. The most common side effects reported were: constipation , nausea , increased headache , and fatigue .
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My Hair Loss Bothered Me
I was very sensitive about my diminishing blond locks. The majority of my hair thinned out around my temples and ears. I became a master at arranging hair from the top of my head to cover the patchy balding spots. Ponytails made the issue very obvious, so hats became my new favorite accessory. Even if other people didnt notice, it really bothered me.
Serious Side Effects Of Aimovig
Aimovig may cause serious side effects in some people. The list below may not include all the possible serious side effects of the drug. For more information, you can refer to Aimovigs patient information.
The Food and Drug Administration approved Aimovig in 2018. So far, the drug hasnt been known to cause any long-term side effects.
If you develop serious side effects while using Aimovig, call your doctor right away. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number.
Serious side effects that have been reported with Aimovig are explained in more detail below in Side effect specifics. These include:
Aimovig may cause several side effects. Here are some frequently asked questions about the drugs side effects and their answers.
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Does Aimovig Cause Weight Gain Or Weight Loss
Its not likely. Weight changes werent reported as side effects in clinical studies of Aimovig.
However, other drugs used to help prevent migraine episodes may cause weight changes. For example, topiramate is known to cause weight loss. And propranolol could cause weight gain.
If youre concerned about weight changes with Aimovig, talk with your doctor. They can suggest ways to help you manage a weight thats healthy for you.
How Does Aimovig Work
Aimovig is used to help prevent migraine headaches. Migraine is a condition that may cause a severe headache along with other symptoms. These symptoms can include nausea, vomiting, and problems with speech or vision.
Aimovigs mechanism of action is to block the activity of a protein called calcitonin gene-related peptide . CGRP can play a role in causing migraine symptoms. By blocking CGRP, Aimovig helps prevent migraine episodes.
If youd like to know more about how Aimovig works, talk with your doctor or pharmacist.
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Will I Have Withdrawal Symptoms If I Stop Taking Aimovig
No, it isnt likely that youll have withdrawal symptoms if you stop taking Aimovig.
Withdrawal symptoms are side effects that may happen after you suddenly stop taking a drug. But withdrawal symptoms werent reported in studies of Aimovig. Its important to not change or stop your Aimovig treatment without your doctors recommendation, though.
To learn more about what to expect with Aimovig, talk with your doctor or pharmacist.
Aimovig Side Effects And How To Avoid Them
Aimovig side effects | Serious side effects | High blood pressure | Hair loss | Immunogenicity | How long do side effects last? | Warnings | Interactions | How to avoid side effects | Resources
Aimovig is a brand-name prescription drug taken as a once-monthly injection to prevent episodic or chronic migraine headaches. The active ingredient in Aimovig is erenumab-aooe, a monoclonal antibody that blocks the CGRP receptor to prevent inflammation associated with migraines. Although effective at reducing the number of migraine days each month, Aimovig may cause certain side effects, which may be worsened by pre-existing conditions or drug interactions.
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Let Aimovig Warm To Room Temperature Before An Injection
To avoid injection site reactions, dont be hasty when giving an injection. Injecting cold medicine can cause pain and redness. Remove the Aimovig autoinjector or prefilled syringe from the refrigerator about 30 minutes before an injection. Let it stand in the carton protected from light to warm up to room temperature. Dont heat it in any way, just let the ambient room temperature warm it up. After 30 minutes, the medicine should be ready for injection.
Alcohol Use And Aimovig
There arent any known safety issues with drinking alcohol while using Aimovig.
But for some people, drinking alcohol can trigger a migraine episode. If you know alcohol is one of your migraine triggers, youll likely want to avoid alcohol while using the drug.
If you drink alcohol, talk with your doctor about the amount thats safe for you to have while using Aimovig.
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Does Aimovig Cause Anxiety Depression Fatigue Or Hair Loss
No, this isnt likely. Anxiety, depression, fatigue , and hair loss werent reported as side effects in initial studies of Aimovig.
But its important to remember that migraine can cause many different symptoms, including depression and fatigue. Aimovig is used to prevent migraine headaches. So you may have these symptoms while taking the drug. But these symptoms may be related to migraine, not caused by Aimovig itself.
People whove taken Aimovig after it became available for use have reported hair loss.
But hair loss can happen because of stress, and stress can also trigger a migraine headache. So you may have hair loss related to migraine or stress while taking Aimovig. But these symptoms may not be caused by Aimovig itself.
If you have these symptoms with Aimovig, talk with your doctor. They can help figure out if these symptoms might be caused by Aimovig, your condition, or something else such as stress.
What Did Physicians And Patients Say About Trying Aimovig
A study at Dartmouth looked at how well Aimovig worked for patients in the real world. This study showed that after only one month of treatment, most patients reported either no or only minimal response and reduction in monthly Migraine days
However, these results improved with continued treatment over time, and many patients reported decreases in average Migraine days by the sixth month. This indicates that it may take time before some people experience the full benefit.
We asked Dr. Rebecca Burch, Assistant Professor at Harvard Medical School and headache specialist at Brigham and Womens Hospital to tell us about her patients experiences. We are seeing that Aimovig is effective in most of our patients who try it. Early results from our clinics survey of patients who used Aimovig show that around 60-65% of patients experienced at least some benefit, she said.
Whats particularly impressive about this finding is that we are mostly prescribing Aimovig to patients who have tried and failed a number of other treatments. There are several unanswered questions, however, including whether this treatment response will be sustained over time, said Dr. Burch. We are seeing some patients for whom the benefit wears off, so well have to study efficacy again after a period of time.
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