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Can Rituxan Cause Hair Loss

How Quickly Will My Hair Grow Back

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Hair loss after treatment is rarely permanent, but it might take a while to grow back.

Part of your hair is made of a protein called keratin. On average, hair grows at a rate of around 1cm or half an inch a month. However, after lymphoma treatment, you might have a temporary lack of keratin, which can weaken your hair and slow its growth. Once keratin levels return to normal, stronger hair can start to grow. How quickly your hair grows back depends on several factors, including the treatment type you’ve had, your individual response to it and your general health.

  • After chemotherapy, hair follicles recover within a few weeks but it takes a bit longer before you can actually see new hair. Most people notice their hair growing back within 3 to 6 months of finishing chemotherapy, although it can take more or less time. Hair often grows back finer, straighter or curlier, or a different colour from how it used to be. Usually, in time, it returns to how it was before treatment. The change is permanent for a small number of people.
  • After radiotherapy, it usually takes around 2 to 6 months for hair to grow back but it can take longer. Your hair might be curlier or a different texture than it was before treatment. In some cases, the hair loss can be permanent.

Can Anything Make My Hair Grow More Quickly

Some people think that if they rub or massage their scalp, their hair will grow more quickly. There is no evidence that this helps and, in fact, it could damage fragile new hair and so have a negative impact on hair regrowth.

There is some evidence that minoxidil solution might help it grow back faster. However, further research is needed. Speak to your medical team before using any over-the-counter medicines, to check that they are safe for you.

There are no complementary and alternative medicines recommended in the UK to help with treatment-related hair loss. This includes therapies and natural products such as vitamins, minerals and plant-based products.

If you are considering trying something to help your hair to re-grow, check with your medical team first that it is safe for you. Some could irritate your scalp and cause further hair loss.

For Men Using Rituxan

The manufacturer of Rituxan hasnt provided any birth control recommendations for men who take the medication. But if youre a man whos using Rituxan and your sexual partner can become pregnant, talk with your doctor. They can review your birth control needs during and after your Rituxan treatment.

For more information about taking Rituxan during pregnancy, see the Rituxan and pregnancy section above.

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What Are The Possible Side Effects Of Rituxan

Rituxan can cause serious side effects, including:

  • Tumor Lysis Syndrome : TLS is caused by the fast breakdown of cancer cells. TLS can cause you to have:

  • Kidney failure and the need for dialysis treatment
  • Abnormal heart rhythm

TLS can happen within 12 to 24 hours after an infusion of Rituxan. Your healthcare provider may do blood tests to check you for TLS. Your healthcare provider may give you medicine to help prevent TLS.

Tell your healthcare provider right away if you have any of the following signs or symptoms of TLS:

  • nausea
  • diarrhea
  • lack of energy
  • Serious Infections: Serious infections can happen during and after treatment with Rituxan, and can lead to death. Rituxan can increase your risk of getting infections and can lower the ability of your immune system to fight infections. Types of serious infections that can happen with Rituxan include bacterial, fungal, and viral infections. After receiving Rituxan, some people have developed low levels of certain antibodies in their blood for a long period of time . Some of these patients with low antibody levels developed infections. People with serious infections should not receive Rituxan. Tell your healthcare provider right away if you have any symptoms of infection:
  • fever
  • cold symptoms, such as runny nose or sore throat, that do not go away
  • flu symptoms, such as cough, tiredness, and body aches
  • earache or headache
  • cold sores in the mouth or throat
  • cuts, scrapes, or incisions that are red, warm, swollen, or painful
  • A Day In The Life: Grace Receives A Rituxan Infusion

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    Every six months, my 16-year-old daughter, Grace, receives a dose of Rituxan , the latest and greatest treatment we have added to her regimen for Lambert-Eaton myasthenic syndrome .

    Before that first dose, Grace was exhausted all the time. She was able to do very little outside the house because her energy was so low. She could not walk more than a few steps without assistance. Her voice was weak and shaky.

    Grace had responded well to prednisone, but because of the side effects, her doctor wanted her to wean off of it. At that point, her team of doctors thought it most prudent to try Rituxan.

    Although Rituxan is prescribed for LEMS, its effectiveness in LEMS patients has not been tested in clinical trials. However, I can attest to its effectiveness in Grace. Rituxan has made an extraordinary difference. Grace has so much more energy than she did before the treatment. Her stamina has increased and her walking is sturdier. Grace struggled with slurred speech, and that has mostly disappeared. She has gotten big pieces of her life back since beginning this treatment.

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    Raised Levels Of Uric Acid

    This treatment may cause the cancer cells to break down quickly. This releases uric acid into the blood. The kidneys usually get rid of uric acid, but may not be able to cope with large amounts. Too much uric acid can cause swelling and pain in the joints, which is called gout.

    Your doctor may give you drugs to help prevent this. Drinking at least 2 litres of fluid a day will also help. You will have regular blood tests to check the uric acid levels.

    Common Adverse Reactions And Side Effects Of Rituxan

    According to clinical trial data, adverse reactions in patients receiving Rituxan for NHLs include the following, which were found to occur up to 12 months after Rituxan infusion:

    Systemic reactionsMore common: Fever, chills, infections, astheniaLess common: headaches, abdominal pain, back pain

    Lymphatic system reactionsLess common: Leukopenia, neutropenia, thrombocytopenia

    Skin/appendage reactionsMore common: Night sweats, rash, pruritus

    Respiratory reactions:More common: Increased cough, rhinitisLess common: Bronchospasm, dyspnea

    In this case, reports of the so-called “Rituxan cough” seems to be on the rise, and it is one of the side effects of Rituxan worth watching out for.

    Metabolic and nutritional disorders:Less common: Angiodema, hyperglycemia, peripheral edema, LDH increase

    Digestive system reactions:Nausea, and to a lesser extent, diarrhea and vomiting

    There were also small percentages of reports of people experiencing nervous system reactions, musculoskeletal reactions, and cardiovascular system reactions.

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    But Is Saw Palmetto Really Effective At Stopping Hair Loss

    Ultimately, though, the existing studies show finasteride works for more people. Researchers found that, when comparing the two, the finasteride worked to stop hair loss for 68% of participants while saw palmetto extract only boosted hair growth in 38%. However, it should be noted that the medication was more effective in the individuals who had less advanced male pattern baldness 52935-7/fulltext rel=nofollow> another finasteride study shows up to a 90% success rate).

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    Tips To Help Prepare For Hair Loss

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    We give some tips below. However, the approach you decide to take is a very personal decision.

    Consider your options

    Take some time to think about your approach in advance of changes happening this could include what you might say to people, as well as if and how you choose to cover changes to your appearance.

    Some people find it helpful to use an app that shows how you would look without hair. Search online for one thats suitable for your device.

    Tell friends, family and colleagues that you expect to lose your hair

    Letting people know that you might lose your hair can prepare you and them for this possibility. Having this conversation in advance might help to lessen your anxiety about others reactions to any changes in your appearance. You could also signpost them to our information, to help explain hair loss as a side effect of treatment.

    Cut or shave your hair

    Hair loss due to cancer treatment can be less obvious if you cut your hair short or shave it completely. Some people also find this more comfortable. It can also make it easier to fit headwear such as a wig. If you have a beard or moustache, you could also shave these this can help you get used to having less hair and heighten your sense of control over the situation.

    Covering your hair loss

    There are lots of headwear options available. We outline some popular choices below.

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    If Experienced These Tend To Have A Severe Expression I

  • an infection due to a virus
  • pneumonia with a fungus called Pneumocystis jirovecii
  • high amount of phosphate in the blood
  • low amount of calcium in the blood
  • high levels of potassium in the blood
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • a decrease in bone marrow production
  • inflammation of the uvea of the eye
  • sudden blindness and pain upon moving the eye
  • a heart attack
  • angina, a type of chest pain
  • ventricular fibrillation, a heart rhythm disorder
  • abnormal heart rhythm
  • supraventricular arrhythmias, a type of abnormal heart rhythm
  • heart failure
  • inflammation of the blood vessels
  • a type of lung condition called bronchiolitis obliterans
  • pneumonia
  • pleuritis, a condition where the covering of the lung becomes inflamed
  • x-ray results showing lung tissue changes
  • acute respiratory distress syndrome, a type of lung disorder
  • blocked bowels with decreased peristaltic movement
  • blockage of the stomach or intestine
  • a hole in the intestine
  • liver failure
  • pyoderma gangrenosum, a condition where large painful skin sores form
  • inflammation of the skin with blisters
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • a condition with symptoms that resemble lupus
  • muscle weakness of the arms or legs
  • blood circulation failure due to serious heart condition
  • a significant type of allergic reaction called anaphylaxis
  • a serum sickness reaction
  • Which Chemotherapy Drugs Cause Hair Loss

    Your medical team will speak to you about your risk of hair loss before you begin treatment.

    Lymphoma chemotherapy drugs that usually cause hair loss include:

    • doxorubicin
    • ifosphamide
    • conditioning chemotherapy .

    Hair loss is more common with intravenous chemotherapy. Whether or not you lose your hair also depends on the dose of your chemotherapy and how often you have it.

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    Will My Hair Fall Out All At Once

    Not everyone who has treatment for lymphoma experiences hair loss. If you do, your hair usually begins to fall out within a couple of weeks of starting treatment. It usually starts at the top and sides of your head, above your ears. It might fall out gradually, in clumps, or quite quickly. You might notice hair on your pillow or clothes, in your hairbrush, or in the plug hole of your bath or shower. Speak to your medical team for information about what to expect based on the treatment you are having.

    Rituxan Use With Drugs

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    In some cases, Rituxan is used with other drugs to treat your condition:

    • Non-Hodgkin lymphoma. With certain forms of non-Hodgkin lymphoma , you may take Rituxan along with chemotherapy medications such as cyclophosphamide, vincristine, and prednisone .
    • Diffuse large B-cell lymphoma. The diffuse large B-cell lymphoma must not have been treated before. For this purpose, Rituxan is used with the medications cyclophosphamide, doxorubicin, vincristine, and prednisone , or with other chemotherapy drugs called anthracyclines.
    • Chronic lymphocytic leukemia. For chronic lymphocytic leukemia thats CD20-positive and has or hasnt been previously treated, Rituxan is used with fludarabine and cyclophosphamide.
    • Rheumatoid arthritis. For rheumatoid arthritis thats moderate to severe and active, Rituxan is used with methotrexate . Active means that you currently have symptoms.
    • Granulomatosis with polyangiitis and microscopic polyangiitis. For granulomatosis with polyangiitis and microscopic polyangiitis , Rituxan is used with drugs called glucocorticoids. These are a type of steroid medication, and they include prednisone.

    Premedications

    Before each dose of Rituxan, youll likely take medications to help prevent infusion reactions from occurring. These drugs are called premedications, and they usually include acetaminophen and an antihistamine, such as diphenhydramine .

    Drugs to help prevent infections

    Here are answers to some frequently asked questions about Rituxan.

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    Rituxan Active Ingredient And Form

    Rituxan contains the active ingredient rituximab and belongs to a group of medications called monoclonal antibodies.

    Rituxan comes as a liquid solution thats available in two strengths: 100 milligrams per 10 milliliters of solution and 500 mg/50 mL. The medication is given as an intravenous infusion. A healthcare provider will give you Rituxan infusions in a doctors office, clinic, or hospital.

    How To Prepare For Rituxan Infusions

    Rituxan infusions can take hours, so be sure to bring something to help keep you busy while youre receiving your dose. This can include a book to read or games to play. You may also want to pack some snacks in case you get hungry while youre having your treatment.

    Before your infusion, youll be given medications to help decrease your risk for having an infusion reaction when you get your dose. Some of these medications may cause you to feel dizzy or tired, so you shouldnt drive yourself home from treatment. Try to schedule someone to bring you home from your treatment in case you arent feeling well.

    Talk with your doctor about any questions you have about receiving Rituxan.

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    Is Rituxan Used For Itp Or Myasthenia Gravis

    Rituxan isnt currently approved to treat immune thrombocytopenia or myasthenia gravis. But Rituxan may be used off-label to treat these conditions.

    With ITP, your immune system attacks your platelets. And this leads to a low level of platelets in your blood. Having a low platelet level can cause you to bruise or bleed more easily than usual.

    Myasthenia gravis is a condition that prevents your nerve cells from clearly communicating with your muscles. This leads to muscle weakness and trouble with activities such as talking, swallowing, chewing, and walking.

    Studies have shown that Rituxan is an effective treatment for

    To learn more about using Rituxan for these conditions, talk with your doctor.

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